High blood levels of selenium (greater than 100 μg/dL) can result in a condition called selenosis.
Symptoms of selenosis include gastrointestinal upsets, hair loss, white blotchy nails, garlic breath odor, fatigue, irritability, and mild nerve damage.
Selenium toxicity is rare in the U.S. The few reported cases have been associated with industrial accidents and a manufacturing error that led to an excessively high dose of selenium in a supplement.
The Institute of Medicine of the National Academy of Sciences has set a tolerable upper intake level (UL) for selenium at 400 micrograms per day for adults to prevent the risk of developing selenosis.
Tolerable Upper Intake Levels for Selenium for Infants, Children, and Adults
Symptoms of selenosis include gastrointestinal upsets, hair loss, white blotchy nails, garlic breath odor, fatigue, irritability, and mild nerve damage.
Selenium toxicity is rare in the U.S. The few reported cases have been associated with industrial accidents and a manufacturing error that led to an excessively high dose of selenium in a supplement.
The Institute of Medicine of the National Academy of Sciences has set a tolerable upper intake level (UL) for selenium at 400 micrograms per day for adults to prevent the risk of developing selenosis.
Tolerable Upper Intake Levels for Selenium for Infants, Children, and Adults
| Age | Males and Females (μg/day) |
|---|---|
| 0 - 6 months | 45 |
| 7 - 12 months | 60 |
| 1-3 y | 90 |
| 4-8 y | 150 |
| 9-13 y | 280 |
| 14-18 y | 400 |
| 19 y + | 400 |
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